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MARCH 21, 2023

Compared With Morphine, Less Respiratory Depression From Oliceridine in Older Patients

NEW ORLEANS—After replicating earlier observations in younger patients, a new trial has concluded that oliceridine (Olinvyk, Trevena) administration results in significantly less respiratory depression than morphine in healthy older volunteers.

The study found that individuals receiving oliceridine experienced both a significant reduction in respiratory depression over time and a significantly shorter duration of respiratory depression.

“After performing an earlier study between