New Orleans—For the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients.
“At my institution, we reviewed quite a bit of data while trying to create a joint replacement surgery protocol,” said Robert B. Maniker, MD, assistant professor of