SEPTEMBER 29, 2021
Oliceridine for the Management of Acute Surgical Pain in High-Risk Patients
This monograph highlights clinical experience using a G-protein–biased ligand designed to provide comparable analgesia to morphine with reduced risk for adverse events from the perspective of the anesthesiologist, surgeon, and pharmacist in various procedures, including interlaminar decompression, left knee replacement, and laparoscopic cholecystectomy.
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Oliceridine for the Management of Acute Surgical Pain in High-Risk Patients
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Postoperative pain is a function of intra-operative pain.
An ounce of prevention is worth a pound of cure. - Ben Franklin
50 mg IV ketamine 2-5 minutes is that 'ounce.'
Olicerdine is the 'pound.'
Lichtner et al doi.org/10.16/bja.2018.03.031 Nociception persists during deep GA
Frauenknecht et al doi. 10.1111/anae.14582 Opioid inclusive anesthesia fails to prevent postoperative pain
Friedberg doi10.20986/mpl.2021.1004/2021 Friedberg's Triad is a pathway to opioid free anesthesia & better outcomes