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FEBRUARY 5, 2021

Genetic Basis Links Opioids Use, Risk for Major Depressive Disorder, Anxiety

Originally published in our sister publication, Pain Medicine News.

Potential causal connections exist between the genetic liability for increased prescription opioid use and risk for major depressive disorder (MDD) and anxiety and stress-related disorders (ASRD), according to a mendelian randomization analysis.

The two-sample study in JAMA Psychiatry (2020 Nov 11. [Epub ahead of print]. doi: 10.1001/jamapsychiatry.2020.3554) found that even after accounting for chronic pain, “which may