The U.S. Preventive Services Task Force has recommended the use of aspirin for primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) (Ann Intern Med 2016 Apr 12 [Epub ahead of print]).
To reach the CRC recommendation, the task force mainly considered CVD trials in which cancer was a secondary finding, because there were limited data specifically on the effects of aspirin on cancer. From 10 trials (N=103,787), the task