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JUNE 14, 2023

The Frost Series #399

Perioperative Priapism Due to Unreported Tadalafil Use

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Richard K. Kim, MD, MSc
Clinical Assistant Professor
Department of Anesthesiology, Perioperative and Pain Medicine
Stanford University School of Medicine
California
Editor: Karen Sibert, MD

Intraoperative priapism is a rare occurrence.1,2 Possible precipitating factors include:

  • antipsychotic and antidepressant medications;
  • epidural analgesia;
  • propofol-based anesthesia;
  • chronic cocaine use;
  • antihypertensive medications (alpha- and beta-receptor antagonists);
  • hematologic disease, especially sickle cell