Grifols is a global health care company with a 70-year legacy of improving people’s health and well-being through the development of life saving plasma medicines, diagnostics systems and hospital pharmacy products. Caring for people is its commitment that remains unchanged since the company started. Grifols is one of the leading companies in the world in the production of life saving plasma therapies, with a business model based on vertical integration, enabling it to control the entire production cycle, starting with the collection of raw material in the form of plasma through an extensive network of donor centers in the United States, and ending with the finished product.
![]() Edwin J. Cohn & Jose Antonio Grifols at the 4th International Congress of Blood Transfusion, Lisbon, 1951. |
At Grifols, a history of innovation defines our modern-day approach to medicine. More than 70 years ago, a Spanish hematologist named Dr. Jose Antonio Grifols Roig pursued a line of research that would set the stage for contemporary use of human plasma to treat disease. Together with his sons, he founded Laboratorios Grifols in 1940.
At A GlanceAddressGrifols DivisionsBioscience: Specializes in the research, development, production and commercialization of high-quality plasma therapies. Hospital: Specializes in operational solutions for compounding areas in pharmacy. Diagnostic: Provides a comprehensive range of transfusion medicine, hemostasis, and immunoassay solutions for clinical laboratories, blood banks and transfusion centers. ProductsAlbumin (Human), marketed as Albutein® 5%, Albutein® 25% and Plasbumin®–5 and Plasbumin®–25 Alpha1-Proteinase Inhibitor (Human), marketed as Prolastin®-C Antihemophilic Factor/von Willebrand Factor Complex (Human), marketed as Alphanate® Antithrombin III (Human), marketed as Thrombate III® BloodChip® for blood genotyping, Coagulation Factor IX (Human), marketed as AlphaNine® SD DG Gel® cards for blood typing Erytra® and Wadiana® automated blood typing instruments Factor IX Complex, marketed as Profilnine® SD Hyperimmune Globulin Therapy Products:
Immune Globulin Intravenous (Human) or IVIG Immune Globulin Injection (Human) Gri-fill® System 3.0 for compounding sterile preparations Misterium® modular clean room solution Grifols-SencorpWhite inventory management system solutions Phocus® Rx: remote pharmacist validation system for compounding IV preparations Procleix NAT solutions for blood testing |
Among their pioneering achievements, they obtained a patent in Spain for the process of plasma lyophilization, or freeze-drying of human plasma, along with the devices needed to inject plasma into patients who required its therapeutic properties. Shortly after, in 1951, Dr. Jose Antonio Grifols Lucas published the first large-scale clinical data describing the plasmapheresis technique of extracting plasma from donors while returning their red blood cells. Combined with the work of Edwin Cohn, Grifols paved the way for the birth of the plasma fractionation industry as we know it today.
From these auspicious beginnings, Grifols has evolved into an industry leader in the collection, manufacture and marketing of plasma-derived therapies. Through recent acquisitions, Grifols is now the third largest global producer of plasma-derived medicines. Grifols operates the world’s largest plasma collection platform, with 150 source plasma donation centers across the United States.
Grifols has a current capacity of plasma protein fractionation of more than 9 million liters of plasma per year. To accommodate the growing global demand for plasma-derived medicines, Grifols is significantly expanding its three manufacturing sites in Clayton, N.C., Los Angeles and Barcelona, Spain—the company’s global headquarters. The expansions include a new, 185,000-square-foot fractionation facility in Clayton and a new facility in Los Angeles dedicated to the production of immune globulin therapies. The new manufacturing facilities will increase the company’s capacity to fractionate plasma to 12 million liters by 2015.
In addition, last year, Grifols opened a new, state-of-the-art plasma testing laboratory in San Marcos, Texas, where every plasma donation undergoes rigorous scientific analysis before being approved for use in manufacturing. The 72,000-square-foot facility houses the latest technology for conducting sophisticated viral testing, including transcription-mediated amplification to rapidly detect minute levels of viral material in plasma samples. The San Marcos laboratory, together with an existing plasma testing laboratory in Austin, will analyze millions of plasma samples annually.
Grifols is firmly committed to giving patients and health care providers broad access to our products. As Grifols grows, it continues to pursue its mission of improving the health and well-being of people around the world.
![]() IVIG manufacturing plant in Barcelona, Spain, designed by Grifols Engineering. |
This corporate profile was reviewed and approved by Grifols.