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SEPTEMBER 10, 2019

No Difference in Morbidity or Mortality for Restrictive or Liberal Transfusion Policies

Montreal—A restrictive transfusion strategy does not have a significant impact on either morbidity or mortality relative to a liberal transfusion strategy.

The systematic review and meta-analysis also found that the restrictive strategy decreased exposure to packed red blood cells (PRBCs) by more than 30%, while saving approximately 0.2 unit of PRBCs per transfused patient.

“The main objective of our study was to identify, appraise and summarize any evidence to compare restrictive and