San Francisco—Implementation of a quality improvement initiative substantially reduced excessive use of neostigmine while improving train-of-four–guided neostigmine administration. Over a six-month period, the initiative led to a decrease in the mean dose of intraoperative neostigmine from 2.9 to 2.5 mg, researchers reported.
“Preliminary data have shown that these interventions led to a statistically significant reduction in the average neostigmine dose that was