Originally published by our sister publication, Pain Medicine News.
Initiating oxycodone in patients who were being treated for depression with the selective serotonin reuptake inhibitors (ssRIs) paroxetine and fluoxetine resulted in a significantly higher risk for opioid overdose than other ssRIs, in a cohort study of more than 2 million adults in the United States.
“We were interested in investigated factors associated with increased opioid overdose from drug–drug