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NOVEMBER 28, 2017

Intranasal Ketamine or Fentanyl for Children: Similar Analgesia, Disproportionate Side Effects

Intranasal ketamine causes more minor side effects, such as dizziness, than intranasal fentanyl used as analgesia for children with assumed single-extremity fractures, according to researchers.

The double-blind, randomized controlled trial (Acad Emerg Med 2017 Sep 19. [Epub ahead of print], doi:10.1111/acem.13313) in 82 children found that while pain relief was similar at 20 minutes between the two groups, the cumulative number of side effects in the ketamine group (n=41) was 2.2 times higher