New Orleans—A large, retrospective study from Mayo Clinic has concluded that the addition of clonidine to a single-shot interscalene block does not improve the quality of analgesia in patients undergoing total shoulder arthroplasty.
The study has helped clarify an issue that has had its supporters and detractors. The investigators noted, however, that some clinicians may still choose to supplement blocks with the α2-adrenergic agonist, given its relative lack of side